Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM, 10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug. 实验结果 A direct linear correlation was observed between plasma concentrations of edoxaban and the blood coagulation parameters PT ratio and INR across all thromboplastin reagents 实验结果 Accordingly, the values of distributions of peak thrombin over time were significantly different between edoxaban and fondaparinux at the tested molar concentration (0.9 μM)